Human Leukocyte Antigen HLA in Korean patients with Autoimmune Thyroid Diseases

Human Leukocyte Antigen (HLA) in Korean patients with Autoimmune Thyroid Diseases

Association between human leukocyte antigen (HLA) and interferon- induced thyroid diseases in four patients with HCV-related chronic hepatitis.

OBJECTIVES The interferon-alpha (IFN-alpha) therapy for HCV hepatitis may exacerbate or induce underlying thyroid disorders. Besides viral factors, the human leukocyte antigen (HLA) may be an independent risk factor. METHODS We evaluated fifteen patients with HCV chronic hepatitis during a period of 40 months. At the enrollment, all the patients were negative for thyroid disorders, excluding ...

Association between human leukocyte antigen (HLA) and interferon-α induced thyroid diseases in four patients with HCV-related

OBJECTIVES : Th e interferon-α (IFN-α) therapy for HCV hepatitis may exacerbate or induce underlying thyroid disorders. Besides viral factors, the human leukocyte antigen (HLA) may be an independent risk factor. METHODS : We evaluated fi ft een patients with HCV chronic hepatitis during a period of 40 months. At the enrolment, all the patients were negative for thyroid disorders, excluding one ...

Plasma human leukocyte antigen-G (HLA-G) in patients with thyroid cancer

Background/aim: A number of tumor markers detected in the serum or pathological specimens using immunohistochemical methods are used for early detection of malignancies and postoperative follow-up. Human leukocyte antigen-G (HLA-G) is a nonclassic HLA class I molecule. Recent studies suggested a relationship between HLA-G positivity and the stage or the phenotype of the malignancy. In this stud...

Human leukocyte Antigen-DM polymorphisms in autoimmune diseases

Classical MHC class II (MHCII) proteins present peptides for CD4(+) T-cell surveillance and are by far the most prominent risk factor for a number of autoimmune disorders. To date, many studies have shown that this link between particular MHCII alleles and disease depends on the MHCII's particular ability to bind and present certain peptides in specific physiological contexts. However, less att...